allamericanreject: (poutbubble)
Alfred F. Jones || America ([personal profile] allamericanreject) wrote in [community profile] sortinghat_rp2012-10-07 10:25 pm

008

So like. i think i've decided I'm pretty bad at dealing with people forever. especially girls. I mean seriously, I like girls and all, they're wonderful and sweet and beautiful to look at both inside and out.
but i just dont think im any good at/with/for girls.
hm.
any girls got advice for like.
fixing friendships?
or guys too. that'll work.
Seriously. im startin to get annoyed now. but I shouldnt be mad right?
ladyliberty: (I dunno lol)

[personal profile] ladyliberty 2012-10-08 04:25 am (UTC)(link)
Stop looking girls in the spleen and then maybe we can talk.
doctorkishitani: (pic#3484671)

[personal profile] doctorkishitani 2012-10-08 04:57 am (UTC)(link)
If you're looking at their spleens, you could just think of them as boys if that makes things easier for you. I don't think there's much difference between the male and female spleen.
ladyliberty: (Da fuq)

[personal profile] ladyliberty 2012-10-08 05:00 am (UTC)(link)
It's a joke. You know what those are, right smart guy?
doctorkishitani: (pic#3661074)

[personal profile] doctorkishitani 2012-10-08 05:10 am (UTC)(link)
So, I suppose this means that you don't, in fact, want to discuss spleens.
ladyliberty: (Oops?)

[personal profile] ladyliberty 2012-10-08 05:14 am (UTC)(link)
Not really, no.
doctorkishitani: (pic#4718254)

[personal profile] doctorkishitani 2012-10-08 05:15 am (UTC)(link)
Perhaps another time?
doctorkishitani: (pic#3484671)

[personal profile] doctorkishitani 2012-10-08 09:14 pm (UTC)(link)
Do you think so?

I have heard that a number of times.

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doctorkishitani: (pic#3265513)

[personal profile] doctorkishitani 2012-10-08 05:11 am (UTC)(link)
Are you sure?

I now understand that this conversation wasn't actually about spleens, but they are fascinating so I wouldn't entirely rule them out as a possible topic of conversation.
doctorkishitani: (pic#3484671)

[personal profile] doctorkishitani 2012-10-08 05:19 am (UTC)(link)
You do have a good point. Spleens are at their best when they are inside bodies. However, you'll never really understand them if you refuse to see them.

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preanimator: (neutral)

[personal profile] preanimator 2012-10-08 05:34 am (UTC)(link)
Actually, there's considerable difference, though I doubt it would be visible to the naked eye. There are some significant sex-related innate differences in the immune response, often driven by various splenic expressions of certain genes. Certain proteins, cell receptors, and enzymes are effected.
doctorkishitani: (pic#3265516)

[personal profile] doctorkishitani 2012-10-08 05:41 am (UTC)(link)
There is? I didn't know that. I suppose my knowledge of the human spleen isn't what it should be at the moment, but I'll read up on it when I next have the opportunity!

Do you know what causes these differences? I imagine it might have to do with hormones, but I can't be sure at this point.
preanimator: (happy thoughts)

[personal profile] preanimator 2012-10-08 05:46 am (UTC)(link)
Yes, it's hormonally based. Testosterone and estrogen have different effects on both the spleen and the immune system in general. For example, the development of erythroid colonies in the spleen is strongly influenced by testosterone.

Most of the studies on it have been done primarily in rats, unfortunately. I would like to see some of these principles tested on humans.
doctorkishitani: (pic#3484671)

[personal profile] doctorkishitani 2012-10-08 05:56 am (UTC)(link)
That did seem to make the most sense. And now that I'm thinking on it, hormone's probably have subtle affects on just about just about every aspect of the human body. I'll try to look into hormonal influences after I've finished researching erythroid colony development.

And you're right! It would be fascinating to see these studies performed on human subjects, but I imagine they might be having trouble finding volunteers. The studies wouldn't be at all effective if the were performed on cadavers, would they?
preanimator: (thinking)

[personal profile] preanimator 2012-10-08 05:59 am (UTC)(link)
Immune function can hardly be studied in a dead body. Well, not yet, anyway. But I have some texts I could lend you, if you're interested, in the systemic effects of various hormones and regulatory cytokines.

I've never personally understood why some people are reluctant to assist with research. Though honestly, you can get lots of subjects if you offer to pay them. Unfortunately, that's considered 'unethical', which sounds like rubbish to me. There's nothing wrong with compensating someone for their time.

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ladyliberty: ('3')

[personal profile] ladyliberty 2012-10-08 05:06 am (UTC)(link)
I dunno, it's on the inside somewhere. I just like the word. Spleen.

But seriously though you ever think maybe actin' like girls are some kinda different species or works of art or somethin' is your problem? They're just people.
ladyliberty: (Dem's fightin' words)

[personal profile] ladyliberty 2012-10-08 05:14 am (UTC)(link)
I'd rather you not lump me in with them either.
ladyliberty: ('3')

[personal profile] ladyliberty 2012-10-08 05:18 am (UTC)(link)
Vicky and I aren't. But it's not like we're anything alike, anyway.

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